Thyroid Cancer Staging

Score Calculator

MACIS Prognostic Score for Papillary Thyroid Carcinoma
Age
Diameter of Tumor (cm)
Complete Resection	No Yes
Local / Vascular Invasion	No Yes
Distant Metastasis	No Yes

MACIS Score
20-Year Survival Rate

References: Hay ID, Bergstralh EJ, Goellner JR, Ebersold JR, Grant CS. Predicting outcome in papillary thyroid carcinoma: development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989. Surgery. 1993 Dec;114(6):1050-7; discussion 1057-8.

The final prognostic score was defined as:
MACIS = 3.1 (if aged less than or equal to 39 years) or 0.08 x age (if aged greater than or equal to 40 years), + 0.3 x tumor size (in centimeters), +1 (if incompletely resected), +1 (if locally invasive), +3 (if distant metastases present).
Twenty-year cause-specific survival rates for patients with:
MACIS < 6: 99%
MACIS 6-6.99: 89%
MACIS 7-7.99: 56%
MACIS 8+: 24%